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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PAX4 Antibody   

PAX4 Antibody

Purified Mouse Monoclonal Antibody

  • E - PAX4 Antibody AO1507a

    Red: Control Antigen (100ng);
    Purple: Antigen (10ng);
    Green: Antigen (50ng);
    Blue: Antigen (100ng);

  • WB - PAX4 Antibody AO1507a
    Figure 1: Western blot analysis using PAX4 mAb against HEK293 (1) and PAX4(AA: 105-232)-hIgGFc transfected HEK293 (2) cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43316
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 3C12
Isotype IgG1
Calculated MW 38kDa
Description This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The paired box 4 gene is involved in pancreatic islet development and mouse studies have demonstrated a role for this gene in differentiation of insulin-producing beta cells.
Immunogen Purified recombinant fragment of human PAX4 expressed in E. Coli.
Formulation Ascitic fluid containing 0.03% sodium azide.
Additional Information
Gene ID 5078
Other Names Paired box protein Pax-4, PAX4
Dilution E~~1/10000
WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPAX4 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PAX4
Function Plays an important role in the differentiation and development of pancreatic islet beta cells. Transcriptional repressor that binds to a common element in the glucagon, insulin and somatostatin promoters. Competes with PAX6 for this same promoter binding site. Isoform 2 appears to be a dominant negative form antagonizing PAX4 transcriptional activity.
Cellular Location Nucleus.
Research Areas
Citations (0)

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1. PLoS One. 2008 Mar 12;3(3):e1783. 2. Diabetes Res Clin Pract. 2008 Sep;81(3):365-9.

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$ 385.00
Cat# AO1507a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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