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MMP3 Antibody

Purified Mouse Monoclonal Antibody

  • E - MMP3 Antibody AO1661a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - MMP3 Antibody AO1661a
    Figure 1: Western blot analysis using MMP3 mAb against human MMP3 (AA: 189-441) recombinant protein. (Expected MW is 54 kDa)
  • FC - MMP3 Antibody AO1661a
    Figure 2: Flow cytometric analysis of NIH/3T3 cells using MMP3 mouse mAb (green) and negative control (red).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08254
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4F10
Isotype IgG1
Calculated MW 54kDa
Description Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Immunogen Purified recombinant fragment of human MMP3 expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 4314
Other Names Stromelysin-1, SL-1,, Matrix metalloproteinase-3, MMP-3, Transin-1, MMP3, STMY1
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMMP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MMP3
Synonyms STMY1
Function Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
Cellular Location Secreted, extracellular space, extracellular matrix
Research Areas
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1. Int J Cancer. 2009 May 1;124(9):2172-8. 2. Cancer Epidemiol Biomarkers Prev. 2008 Dec;17(12):3551-7.

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$ 385.00
Cat# AO1661a
(40 western blots)
Availability: 7-10 days
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