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LPA Antibody

Purified Mouse Monoclonal Antibody

     
  • E - LPA Antibody AO1730a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

    detail
  • WB - LPA Antibody AO1730a
    Figure 1: Western blot analysis using LPA mAb against human LPA recombinant protein. (Expected MW is 34.1 kDa)
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  • IHC - LPA Antibody AO1730a
    Figure 2: Immunohistochemical analysis of paraffin-embedded liver cancer tissues using LPA mouse mAb with DAB staining.
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  • IHC - LPA Antibody AO1730a
    Figure 3: Immunohistochemical analysis of paraffin-embedded breast cancer tissues using LPA mouse mAb with DAB staining.
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  • IHC - LPA Antibody AO1730a
    Figure 4: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using LPA mouse mAb with DAB staining.
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  • IF - LPA Antibody AO1730a
    Figure 5: Immunofluorescence analysis of HepG2 cells using LPA mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, ICC, E
Primary Accession P08519.1
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4H1
Isotype IgG1
Calculated MW 501kDa
Description The protein encoded by this gene is a serine proteinase that inhibits the activity of tissue-type plasminogen activator I. The encoded protein constitutes a substantial portion of lipoprotein(a) and is proteolytically cleaved, resulting in fragments that attach to atherosclerotic lesions and promote thrombogenesis. Elevated plasma levels of this protein are linked to atherosclerosis. Depending on the individual, the encoded protein contains 2-43 copies of kringle-type domains. The allele represented here contains 15 copies of the kringle-type repeats and corresponds to that found in the reference genome sequence.
Immunogen Purified recombinant fragment of human LPA (AA: 4330-4521) expressed in E. Coli.

Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
IF~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLPA Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Research Areas
Citations (0)
citation

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References

1.J Lipid Res. 2010 Oct;51(10):3055-61. 2.Thromb Res. 2010 Sep;126(3):222-6.

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$ 385.00
Cat# AO1730a
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