|Application ||WB, IHC, FC, ICC, E|
|Description||This gene encodes an orphan nuclear receptor which is a member of the nuclear hormone receptor family. Its expression pattern suggests that it may be involved in neurogenesis and germ cell development. The protein can homodimerize and bind DNA, but in vivo targets have not been identified. The gene expresses at least alternatively spliced transcript variants.|
|Immunogen||Purified recombinant fragment of human NR6A1 (AA: 65-118) expressed in E. Coli.|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||Nuclear receptor subfamily 6 group A member 1, Germ cell nuclear factor, GCNF, hGCNF, Retinoid receptor-related testis-specific receptor, RTR, hRTR, NR6A1, GCNF|
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NR6A1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis (By similarity).|
|Tissue Location||Shows highest expression in the germ cells of the adult testis.|
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Provided below are standard protocols that you may find useful for product applications.
1.Biochem Biophys Res Commun. 2010 Dec 10;403(2):178-83.2.Cell. 2005 Sep 23;122(6):957-68.
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