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WDR66 Antibody

Purified Mouse Monoclonal Antibody

  • E - WDR66 Antibody AO1793a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - WDR66 Antibody AO1793a
    Figure 1: Western blot analysis using WDR66 mAb against human WDR66 recombinant protein. (Expected MW is 53.9 kDa)
  • WB - WDR66 Antibody AO1793a
    Figure 2: Western blot analysis using WDR66 mAb against HEK293 (1) and WDR66 (AA: 1-250)-hIgGFc transfected HEK293 (2) cell lysate.
  • FC - WDR66 Antibody AO1793a
    Figure 3: Flow cytometric analysis of HepG2 cells using WDR66 mouse mAb (green) and negative control (purple).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TBY9
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 2A6F7
Isotype IgG1
Calculated MW 130kDa
Description This protein encoded by this gene belongs to the WD repeat-containing family of proteins, which function in the formation of protein-protein complexes in a variety of biological pathways. This family member appears to function in the determination of mean platelet volume (MPV), and polymorphisms in this gene have been associated with variance in MPV. Alternative splicing of this gene results in multiple transcript variants.
Immunogen Purified recombinant fragment of human WDR66 (AA: 1-250) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 144406
Other Names WD repeat-containing protein 66, WDR66
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsWDR66 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name WDR66
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. ;


1. J Genet. 2012 Feb 29;91(1):e1-e11. 2. Cell Mol Life Sci. 2001 Dec;58(14):2085-97.

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$ 385.00
Cat# AO1793a
(40 western blots)
Availability: 7-10 days
Bulk Size
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