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>   home   >   Products   >   Primary Antibodies   >   Neuroscience   >   CD7 Antibody   

CD7 Antibody

Purified Mouse Monoclonal Antibody

     
  • E - CD7 Antibody AO1806a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - CD7 Antibody AO1806a
    Figure 1: Western blot analysis using CD7 mAb against human CD7 recombinant protein. (Expected MW is 36.6 kDa)
  • WB - CD7 Antibody AO1806a
    Figure 2: Western blot analysis using CD7 mAb against HEK293 (1) and CD7 (AA: 72-175)-hIgGFc transfected HEK293 (2) cell lysate.
  • FC - CD7 Antibody AO1806a
    Figure 3: Flow cytometric analysis of Jurkat cells using CD7 mouse mAb (green) and negative control (red).
  • IHC - CD7 Antibody AO1806a
    Figure 5: Immunohistochemical analysis of paraffin-embedded lung cancer tissues using CD7 mouse mAb with DAB staining.
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, FC, E
Primary Accession P09564
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 4D4F8
Isotype IgG1
Calculated MW 25.4kDa
Description This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.
Immunogen Purified recombinant fragment of human CD7 (AA: 72-175) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Other Names T-cell antigen CD7, GP40, T-cell leukemia antigen, T-cell surface antigen Leu-9, TP41, CD7, CD7
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD7
Function Not yet known.
Cellular Location Membrane; Single-pass type I membrane protein EMBL; X06180; CAA29546.1; -; mRNA EMBL; M37271; AAA51953.1; -; Genomic_DNA EMBL; BT006696; AAP35342.1; -; mRNA EMBL; BC009293; AAH09293.1; -; mRNA EMBL; BC013297; AAH13297.1; -; mRNA EMBL; D00749; BAA00646.1; -; Genomic_DNA CCDS; CCDS11807.1; - PIR; A39016; A39016 RefSeq; NP_006128.1; NM_006137.6 UniGene; Hs.36972; - ProteinModelPortal; P09564; - SMR; P09564; - BioGrid; 107362; 8 IntAct; P09564; 5 MINT; P09564; - STRING; 9606.ENSP00000312027; - iPTMnet; P09564; - PhosphoSitePlus; P09564; - SwissPalm; P09564; - BioMuta; CD7; - DMDM; 116031; - PaxDb; P09564; - PeptideAtlas; P09564; - PRIDE; P09564; - ProteomicsDB; 52247; - DNASU; 924; - Ensembl; ENST00000312648; ENSP00000312027; ENSG00000173762 GeneID; 924; - KEGG; hsa:924; - CTD; 924; - DisGeNET; 924; - EuPathDB; HostDB:ENSG00000173762.7; - GeneCards; CD7; - HGNC; HGNC:1695; CD7 HPA; CAB002594; - HPA; HPA039079; - MIM; 186820; gene neXtProt; NX_P09564; - OpenTargets; ENSG00000173762; - PharmGKB; PA26234; - eggNOG; ENOG410IYNZ; Eukaryota eggNOG; ENOG41117EQ; LUCA GeneTree; ENSGT00390000013965; - HOGENOM; HOG000285979; - HOVERGEN; HBG005290; - InParanoid; P09564; - KO; K06457; - OMA; YEDMSHS; - OrthoDB; EOG091G0Q1Y; - PhylomeDB; P09564; - TreeFam; TF338565; - SignaLink; P09564; - GeneWiki; CD7; - GenomeRNAi; 924; - PRO; PR:P09564; - Proteomes; UP000005640; Chromosome 17 Bgee; ENSG00000173762; - CleanEx; HS_CD7; - ExpressionAtlas; P09564; baseline and differential Genevisible; P09564; HS GO; GO:0016021; C:integral component of membrane; TAS:UniProtKB GO; GO:0016020; C:membrane; TAS:ProtInc GO; GO:0005886; C:plasma membrane; TAS:ProtInc GO; GO:0038023; F:signaling receptor activity; TAS:UniProtKB GO; GO:0002250; P:adaptive immune response; IEA:UniProtKB-KW GO; GO:0006955; P:immune response; TAS:UniProtKB GO; GO:0042110; P:T cell activation; TAS:UniProtKB GO; GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; NAS:UniProtKB Gene3D; 2.60.40.10; -; 1 InterPro; IPR039090; CD7 InterPro; IPR007110; Ig-like_dom InterPro; IPR036179; Ig-like_dom_sf InterPro; IPR013783; Ig-like_fold InterPro; IPR003599; Ig_sub InterPro; IPR013106; Ig_V-set PANTHER; PTHR15343; PTHR15343; 1 Pfam; PF07686; V-set; 1 SMART; SM00409; IG; 1 SMART; SM00406; IGv; 1 SUPFAM; SSF48726; SSF48726; 1 PROSITE; PS50835; IG_LIKE; 1 1: Evidence at protein level; Adaptive immunity; Complete proteome; Disulfide bond; Glycoprotein; Immunity; Immunoglobulin domain; Lipoprotein; Membrane; Palmitate; Polymorphism; Receptor; Reference proteome; Repeat; Signal; Transmembrane; Transmembrane helix SIGNAL 1 25 CHAIN 26 240 T-cell antigen CD7 /FTId=PRO_0000014633 TOPO_DOM 26 180 Extracellular TRANSMEM 181 201 Helical. TOPO_DOM 202 240 Cytoplasmic DOMAIN 26 130 Ig-like REPEAT 145 153 1 REPEAT 154 162 2 REPEAT 163 171 3 REPEAT 172 180 4 REGION 145 180 4 X 9 AA tandem repeats, potential spacer function LIPID 198 198 S-palmitoyl cysteine CARBOHYD 45 45 N-linked (GlcNAc...) asparagine CARBOHYD 96 96 N-linked (GlcNAc...) asparagine DISULFID 35 142 {ECO:0000255|PROSITE-ProRule:PRU00114} DISULFID 48 114 {ECO:0000255|PROSITE-ProRule:PRU00114} VARIANT 113 113 T -> A (in dbSNP:rs34579511) /FTId=VAR_049855 SEQUENCE 240 AA; 25409 MW; EBBCE08279552108 CRC64; MAGPPRLLLL PLLLALARGL PGALAAQEVQ QSPHCTTVPV GASVNITCST SGGLRGIYLR QLGPQPQDII YYEDGVVPTT DRRFRGRIDF SGSQDNLTIT MHRLQLSDTG TYTCQAITEV NVYGSGTLVL VTEEQSQGWH RCSDAPPRAS ALPAPPTGSA LPDPQTASAL PDPPAASALP AALAVISFLL GLGLGVACVL ARTQIKKLCS WRDKNSAACV VYEDMSHSRC NTLSSPNQYQ
Research Areas
Citations (0)

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Background

This gene encodes a transmembrane protein which is a member of the immunoglobulin superfamily. This protein is found on thymocytes and mature T cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development.

References

1.Mol Cancer. 2010 Feb 22;9:41. 2.J Hematol Oncol. 2010 Apr 14;3:15.

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$ 385.00
Cat# AO1806a
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