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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CDX1 Antibody   

CDX1 Antibody

Purified Mouse Monoclonal Antibody

  • E - CDX1 Antibody AO1839a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - CDX1 Antibody AO1839a
    Figure 1: Western blot analysis using CDX1 mAb against human CDX1 recombinant protein. (Expected MW is 37.9 kDa)
  • WB - CDX1 Antibody AO1839a
    Figure 2: Western blot analysis using CDX1 mAb against HEK293 (1) and CDX1 (AA: 122-227)-hIgGFc transfected HEK293 (2) cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P47902
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1B11A9
Isotype IgG2a
Calculated MW 28.1kDa
Description This gene is a member of the caudal-related homeobox transcription factor gene family. The encoded DNA-binding protein regulates intestine-specific gene expression and enterocyte differentiation. It has been shown to induce expression of the intestinal alkaline phosphatase gene, and inhibit beta-catenin/T-cell factor transcriptional activity.
Immunogen Purified recombinant fragment of human CDX1 (AA: 122-227) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 1044
Other Names Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1
Dilution E~~1/10000
WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDX1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDX1
Function Could play a role in the terminal differentiation of the intestine.
Cellular Location Nucleus.
Tissue Location Intestinal epithelium.
Research Areas
Citations (0)

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This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments. ;


1. Am J Pathol. 2012 Aug;181(2):487-98. 2. J Korean Med Sci. 2011 May;26(5):647-53.

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$ 385.00
Cat# AO1839a
(40 western blots)
Availability: 7-10 days
Bulk Size
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