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SYCP3 Antibody

Purified Mouse Monoclonal Antibody

  • E - SYCP3 Antibody AO1856a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - SYCP3 Antibody AO1856a
    Figure 1: Western blot analysis using SYCP3 mAb against human SYCP3 recombinant protein. (Expected MW is 37.2 kDa)
  • WB - SYCP3 Antibody AO1856a
    Figure 2: Western blot analysis using SYCP3 mAb against HEK293 (1) and SYCP3 (AA: 27-128)-hIgGFc transfected HEK293 (2) cell lysate.
  • IF - SYCP3 Antibody AO1856a
    Figure 3: Immunofluorescence analysis of HepG2 cells using SYCP3 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.
  • FC - SYCP3 Antibody AO1856a
    Figure 4: Flow cytometric analysis of Jurkat cells using SYCP3 mouse mAb (green) and negative control (red).
  • IHC - SYCP3 Antibody AO1856a
    Figure 5: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using SYCP3 mouse mAb with DAB staining.
  • IHC - SYCP3 Antibody AO1856a
    Figure 6: Immunohistochemical analysis of paraffin-embedded kidney tissues using SYCP3 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8IZU3
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6F9C5
Isotype IgG1
Calculated MW 27.7kDa
Description This gene encodes an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. Mutations in this gene are associated with azoospermia in males and susceptibility to pregnancy loss in females. Alternate splicing results in multiple transcript variants that encode the same protein.
Immunogen Purified recombinant fragment of human SYCP3 (AA: 27-128) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 50511
Other Names Synaptonemal complex protein 3, SCP-3, SYCP3, SCP3
Dilution E~~1/10000
WB~~1/500 - 1/2000
IF~~1/200 - 1/1000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSYCP3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SYCP3
Synonyms SCP3
Function Component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase. Has an essential meiotic function in spermatogenesis. May be important for testis development. Required for efficient phosphorylation of HORMAD1 and HORMAD2 (By similarity).
Cellular Location Nucleus. Chromosome. Note=In tripartite segments of synaptonemal complexes, irrespective of whether these are synapsed or unsynapsed.
Tissue Location Testis-specific.
Research Areas
Citations (0)

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There are three proteins including thyroxine-binding globulin (TBG), transthyretin and albumin responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3'-triiodothyronine (T3) in the bloodstream. This gene encodes the major thyroid hormone transport protein, TBG, in serum. It belongs to the serpin family in genomics, but the protein has no inhibitory function like many other members of the serpin family. Mutations in this gene result in TGB deficiency, which has been classified as partial deficiency, complete deficiency, and excess, based on the level of serum TBG. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. ;


1. Hum Pathol. 2013 Apr;44(4):472-9. 2. Cytogenet Genome Res. 2010;128(1-3):162-8.

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$ 385.00
Cat# AO1856a
(40 western blots)
Availability: 7-10 days
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