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CNN1 Antibody

Purified Mouse Monoclonal Antibody

  • E - CNN1 Antibody AO1932a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - CNN1 Antibody AO1932a
    Figure 1: Western blot analysis using CNN1 mAb against human CNN1 (AA: 16-165) recombinant protein. (Expected MW is 43.1 kDa)
  • WB - CNN1 Antibody AO1932a
    Figure 2: Western blot analysis using CNN1 mAb against HEK293 (1) and CNN1 (AA: 16-165)-hIgGFc transfected HEK293 (2) cell lysate.
  • IHC - CNN1 Antibody AO1932a
    Figure 3: Immunohistochemical analysis of paraffin-embedded cervical cancer tissues using CNN1 mouse mAb with DAB staining.
  • IHC - CNN1 Antibody AO1932a
    Figure 4: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CNN1 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51911
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1H5B5
Isotype IgG1
Calculated MW 33.2kDa
Description Calponin h1 (CN) is a differentiation marker of smooth muscle cells that has been reported to be down-regulated in the blood vessels of several human tumors.
Immunogen Purified recombinant fragment of human CNN1 (AA: 16-165) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 1264
Other Names Calponin-1, Basic calponin, Calponin H1, smooth muscle, CNN1
Dilution E~~1/10000
WB~~1/500 - 1/2000
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCNN1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CNN1
Function Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity (By similarity).
Tissue Location Smooth muscle, and tissues containing significant amounts of smooth muscle
Research Areas
Citations (0)

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Chromobox homolog 8 (CBX8), a Polycomb Group protein that interacts with MLL-AF9 and TIP60, plays an essential role in MLL-AF9 transcriptional regulation and leukemogenesis. CBX8, which is part of one of the PRC1 complexes, regulates proliferation of diploid human and mouse fibroblasts through direct binding to the INK4A-ARF locus. ; ;


1. Anticancer Res. 2010 Apr;30(4):1071-8.2. Eur J Surg Oncol. 2008 May;34(5):531-7.

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$ 325.00
Cat# AO1932a
(40 western blots)
Availability: 7-10 days
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