|Application ||WB, IHC, FC, E|
|Description||This gene encodes a member of the tubulin superfamily. This protein localizes to the centriolar sub-distal appendages that are associated with the older of the two centrioles after centrosome duplication. This protein plays a central role in organization of the microtubules during centriole duplication. A pseudogene of this gene is found on chromosome 5.|
|Immunogen||Purified recombinant fragment of human TUBE1 (AA: 314-472) expressed in E. Coli.|
|Formulation||Purified antibody in PBS with 0.05% sodium azide.|
|Other Names||Tubulin epsilon chain, Epsilon-tubulin, TUBE1, TUBE|
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TUBE1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=Associated with pericentriolar material|
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The innate immune system confers host defense against viral and microbial infection, and TRAFD1 is a negative feedback regulator that controls excessive immune responses ; ;
1. Nat Cell Biol. 2003 Jan;5(1):71-6.2. Nat Cell Biol. 2000 Jan;2(1):30-5.
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