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SERPINA3 Antibody

Purified Mouse Monoclonal Antibody

  • E - SERPINA3 Antibody AO1978a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - SERPINA3 Antibody AO1978a
    Figure 1: Western blot analysis using SERPINA3 mAb against human SERPINA3 (AA: 279-432) recombinant protein. (Expected MW is 42.3 kDa)
  • WB - SERPINA3 Antibody AO1978a
    Figure 2: Western blot analysis using SERPINA3 mAb against HEK293 (1) and SERPINA3 (AA: 279-432)-hIgGFc transfected HEK293 (2) cell lysate.
  • WB - SERPINA3 Antibody AO1978a
    Figure 3: Western blot analysis using SERPINA3 mouse mAb against A549 cell lysate.
  • FC - SERPINA3 Antibody AO1978a
    Figure 4: Flow cytometric analysis of A549 cells using SERPINA3 mouse mAb (green) and negative control (red).
  • IHC - SERPINA3 Antibody AO1978a
    Figure 5: Immunohistochemical analysis of paraffin-embedded endometrial cancer tissues using SERPINA3 mouse mAb with DAB staining.
  • IHC - SERPINA3 Antibody AO1978a
    Figure 6: Immunohistochemical analysis of paraffin-embedded bladder cancer tissues using SERPINA3 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P01011
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 5G3C11
Isotype IgG1
Calculated MW 47.7kDa
Description The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.
Immunogen Purified recombinant fragment of human SERPINA3 (AA: 279-432) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 12
Other Names Alpha-1-antichymotrypsin, ACT, Cell growth-inhibiting gene 24/25 protein, Serpin A3, Alpha-1-antichymotrypsin His-Pro-less, SERPINA3, AACT
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSERPINA3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms AACT
Function Although its physiological function is unclear, it can inhibit neutrophil cathepsin G and mast cell chymase, both of which can convert angiotensin-1 to the active angiotensin-2.
Cellular Location Secreted.
Tissue Location Plasma. Synthesized in the liver. Like the related alpha-1-antitrypsin, its concentration increases in the acute phase of inflammation or infection. Found in the amyloid plaques from the hippocampus of Alzheimer disease brains
Research Areas
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DNAL4 is a component of the dynein motor complex


1. Cerebrovasc Dis. 2010;29(1):68-72. 2. Cerebrovasc Dis. 2007;23(1):46-9.

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$ 385.00
Cat# AO1978a
(40 western blots)
Availability: 7-10 days
Bulk Size
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