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CD6 Antibody

Purified Mouse Monoclonal Antibody

  • E - CD6 Antibody AO1996a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - CD6 Antibody AO1996a
    Figure 1: Western blot analysis using CD6 mAb against human CD6 (AA: Extra(18-199)) recombinant protein. (Expected MW is 44.8 kDa)
  • WB - CD6 Antibody AO1996a
    Figure 2: Western blot analysis using CD6 mAb against HEK293 (1) and CD6 (AA: Extra(18-199))-hIgGFc transfected HEK293 (2) cell lysate.
  • FC - CD6 Antibody AO1996a
    Figure 3: Flow cytometric analysis of Hela cells using CD6 mouse mAb (green) and negative control (red).
  • IHC - CD6 Antibody AO1996a
    Figure 4: Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CD6 mouse mAb with DAB staining.
  • IHC - CD6 Antibody AO1996a
    Figure 5: Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using CD6 mouse mAb with DAB staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P30203
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6B11G6
Isotype IgG2b
Calculated MW 71.8kDa
Description This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation. This gene may be associated with susceptibility to multiple sclerosis (PMID: 19525953, 21849685). Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Purified recombinant fragment of human CD6 (AA: Extra(18-199)) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide.
Additional Information
Gene ID 923
Other Names T-cell differentiation antigen CD6, T12, TP120, CD6, CD6
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CD6
Function Involved in cell adhesion. Binds to CD166.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed by thymocytes, mature T-cells, a subset of B-cells known as B-1 cells, and by some cells in the brain
Research Areas
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1. J Autoimmun. 2010 Dec;35(4):336-41.2. Proc Natl Acad Sci U S A. 2007 Jul 10;104(28):11724-9.

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$ 385.00
Cat# AO1996a
(40 western blots)
Availability: 7-10 days
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