|Application ||WB, IHC, FC, ICC, E|
|Description||CBX6 (chromobox homolog 6) is a protein-coding gene. GO annotations related to this gene include single-stranded RNA binding. An important paralog of this gene is CBX8.|
|Immunogen||Purified recombinant fragment of human CBX6 (AA: 269-412) expressed in E. Coli.|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||Chromobox protein homolog 6, CBX6|
WB~~1/500 - 1/2000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CBX6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.|
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1.J Biol Chem. 2011 Jan 7;286(1):521-9.
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