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CBX6 Antibody

Purified Mouse Monoclonal Antibody

  • E - CBX6 Antibody AO2075a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - CBX6 Antibody AO2075a

    Figure 2:Western blot analysis using CBX6 mAb against human CBX6 (AA: 269-412) recombinant protein. (Expected MW is 40.3 kDa)

  • WB - CBX6 Antibody AO2075a

    Figure 3:Western blot analysis using CBX6 mAb against HEK293 (1) and CBX6 (AA: 269-412)-hIgGFc transfected HEK293 (2) cell lysate.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95503
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 8D10A3
Isotype IgG1
Calculated MW 43.9kDa
Description CBX6 (chromobox homolog 6) is a protein-coding gene. GO annotations related to this gene include single-stranded RNA binding. An important paralog of this gene is CBX8.
Immunogen Purified recombinant fragment of human CBX6 (AA: 269-412) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 23466
Other Names Chromobox protein homolog 6, CBX6
Dilution E~~1/10000
WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCBX6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CBX6
Function Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Cellular Location Nucleus.
Citations (0)

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1.J Biol Chem. 2011 Jan 7;286(1):521-9.

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$ 385.00
Cat# AO2075a
(40 western blots)
Availability: 7-10 days
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