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BMP7 Antibody

Purified Mouse Monoclonal Antibody

  • E - BMP7 Antibody AO2133a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - BMP7 Antibody AO2133a

    Figure 2:Western blot analysis using BMP7 mAb against human BMP7 (AA: 239-431) recombinant protein. (Expected MW is 47.7 kDa)

  • WB - BMP7 Antibody AO2133a

    Figure 3:Western blot analysis using BMP7 mAb against HEK293 (1) and BMP7 (AA: 239-431)-hIgGFc transfected HEK293 (2) cell lysate.

  • WB - BMP7 Antibody AO2133a

    Figure 4:Western blot analysis using BMP7 mouse mAb against Raw264.7 (1), A549 (2), Jurkat (3), PC-3 (4), HEK293 (5), Jurkat (6), NIH/3T3 (7), and Hela (8) cell lysate.

  • FC - BMP7 Antibody AO2133a

    Figure 5:Flow cytometric analysis of HEK293 cells using BMP7 mouse mAb (green) and negative control (red).

  • IHC - BMP7 Antibody AO2133a

    Figure 6:Immunohistochemical analysis of paraffin-embedded esophageal cancer tissues using BMP7 mouse mAb with DAB staining.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P18075
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Clone Names 6E5D12
Isotype IgG1
Calculated MW 49.3kDa
Description The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development and possible bone inductive activity.
Immunogen Purified recombinant fragment of human BMP7 (AA: 239-431) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 655
Other Names Bone morphogenetic protein 7, BMP-7, Osteogenic protein 1, OP-1, Eptotermin alfa, BMP7, OP1
Dilution E~~1/10000
WB~~1/500 - 1/2000
FC~~1/200 - 1/400
IHC~~1/200 - 1/1000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBMP7 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMP7
Synonyms OP1
Function Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Cellular Location Secreted.
Tissue Location Expressed in the kidney and bladder. Lower levels seen in the brain
Research Areas
Citations (0)

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1.Immunol Cell Biol. 2014 May-Jun;92(5):427-35.2.J Exp Med. 2013 Nov 18;210(12):2597-610.

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$ 385.00
Cat# AO2133a
(40 western blots)
Availability: 7-10 days
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