|Application ||WB, E|
|Description||This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis.|
|Immunogen||Purified recombinant fragment of human KLF6 (AA: 71-283) expressed in E. Coli.|
|Formulation||Purified antibody in PBS with 0.05% sodium azide|
|Other Names||Krueppel-like factor 6, B-cell-derived protein 1, Core promoter element-binding protein, GC-rich sites-binding factor GBF, Proto-oncogene BCD1, Suppressor of tumorigenicity 12 protein, Transcription factor Zf9, KLF6, BCD1, COPEB, CPBP, ST12|
WB~~1/500 - 1/2000
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLF6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||BCD1, COPEB, CPBP, ST12|
|Function||Transcriptional activator (By similarity). Binds a GC box motif. Could play a role in B-cell growth and development.|
|Tissue Location||Highly expressed in placenta followed by spleen, thymus, prostate, testis, small intestine and colon Weakly expressed in pancreas, lung, liver, heart and skeletal muscle. Also expressed in fetal brain, spleen and thymus|
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1.Tumour Biol. 2013 Apr;34(2):1097-105.2.Int Orthop. 2012 Oct;36(10):2107-11.
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