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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SH3GL1 Antibody   

SH3GL1 Antibody

Purified Mouse Monoclonal Antibody

  • E - SH3GL1 Antibody AO2218a

    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

  • WB - SH3GL1 Antibody AO2218a

    Figure 2:Western blot analysis using SH3GL1 mAb against human SH3GL1 (AA: 12-119) recombinant protein. (Expected MW is 37.6 kDa)

  • WB - SH3GL1 Antibody AO2218a

    Figure 3:Western blot analysis using SH3GL1 mAb against HEK293 (1) and SH3GL1 (AA: 12-119)-hIgGFc transfected HEK293 (2) cell lysate.

  • WB - SH3GL1 Antibody AO2218a

    Figure 4:Western blot analysis using SH3GL1 mouse mAb against HepG2 (1), A549 (2), HT-29 (3), and PC-12 (4) cell lysate.

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q99961
Reactivity Human, Rat
Host Mouse
Clonality Monoclonal
Clone Names 4B4C2
Isotype IgG1
Calculated MW 41.5kDa
Description This gene encodes a member of the endophilin family of Src homology 3 domain-containing proteins. The encoded protein is involved in endocytosis and may also play a role in the cell cycle. Overexpression of this gene may play a role in leukemogenesis, and the encoded protein has been implicated in acute myeloid leukemia as a fusion partner of the myeloid-lymphoid leukemia protein. Pseudogenes of this gene are located on the long arm of chromosomes 11 and 17. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen Purified recombinant fragment of human SH3GL1 (AA: 12-119) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 6455
Other Names Endophilin-A2, EEN fusion partner of MLL, Endophilin-2, Extra eleven-nineteen leukemia fusion gene protein, EEN, SH3 domain protein 2B, SH3 domain-containing GRB2-like protein 1, SH3GL1, CNSA1, SH3D2B
Dilution E~~1/10000
WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSH3GL1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SH3GL1
Synonyms CNSA1, SH3D2B
Function Implicated in endocytosis. May recruit other proteins to membranes with high curvature (By similarity).
Cellular Location Cytoplasm. Early endosome membrane; Peripheral membrane protein Cell projection, podosome Note=Associated with postsynaptic endosomes in hippocampal neurons.
Tissue Location Ubiquitous. Higher expression in pancreas, placenta, prostate, testis and uterus
Research Areas
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1.J Exp Clin Cancer Res. 2012 Oct 11;31:85.2.Mol Med Rep. 2013 Oct;8(4):1111-7.

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$ 385.00
Cat# AO2218a
(40 western blots)
Availability: 7-10 days
Bulk Size
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