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TGFBR3 Antibody

Purified Mouse Monoclonal Antibody

  • E - TGFBR3 Antibody AO2253a

    Black line: Control Antigen (100 ng);
    Purple line: Antigen(10ng);
    Blue line: Antigen (50 ng);
    Red line: Antigen (100 ng);

  • WB - TGFBR3 Antibody AO2253a
    Figure 1: Western blot analysis using TGFBR3 mAb against human TGFBR3 recombinant protein. (Expected MW is 44.1 kDa)
  • WB - TGFBR3 Antibody AO2253a
    Figure 2: Western blot analysis using TGFBR3 mouse mAb against Jurkat (1), HeLa (2), MCF-7 (3), F9 (4), SK-N-SH (5), and NIH3T3 (6) cell lysate.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q03167
Reactivity Human, Mouse
Host Mouse
Clonality Monoclonal
Clone Names 1C5H11
Isotype IgG1
Calculated MW 93.4kDa
Description This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
Immunogen Purified recombinant fragment of human TGFBR3 (AA: 147-328 ) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 7049
Other Names Transforming growth factor beta receptor type 3, TGF-beta receptor type 3, TGFR-3, Betaglycan, Transforming growth factor beta receptor III, TGF-beta receptor type III, TGFBR3
Dilution E~~1/10000
WB~~1/500 - 1/2000
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTGFBR3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.
Cellular Location Secreted. Secreted, extracellular space. Cell membrane; Single-pass type I membrane protein. Note=Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix
Research Areas
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1.Mol Biol Cell. 2011 May;22(9):1463-72. 2.Zhongguo Fei Ai Za Zhi. 2010 May;13(5):451-7.

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$ 385.00
Cat# AO2253a
(40 western blots)
Availability: 7-10 days
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