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CD110

Purified Mouse Monoclonal Antibody

     
  • E - CD110 AO2656a
    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
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  • WB - CD110 AO2656a
    Figure 2:Western blot analysis using CD110 mAb against human CD110 (AA: extra 26-175) recombinant protein. (Expected MW is 47.2 kDa)
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  • WB - CD110 AO2656a
    Figure 3:Western blot analysis using CD110 mAb against HEK293 (1) and CD110 (AA: extra 26-175)-hIgGFc transfected HEK293 (2) cell lysate.
    detail
  • FCM - CD110 AO2656a
    Figure 4:Flow cytometric analysis of K562 cells using CD110 mouse mAb (green) and negative control (red).
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, ICC, E
Primary Accession P40238
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 1D6B7
Isotype Mouse IgG2a
Calculated MW 71.2kDa
Immunogen Purified recombinant fragment of human CD110 (AA: extra 26-175) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 4352
Other Names MPL; MPLV; TPOR; C-MPL; THCYT2
Dilution E~~ 1/10000
WB~~ 1/500 - 1/2000
FCM~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCD110 is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MPL
Synonyms TPOR
Function Receptor for thrombopoietin that acts as a primary regulator of megakaryopoiesis and platelet production. May represent a regulatory molecule specific for TPO-R-dependent immune responses.
Cellular Location Cell membrane; Single-pass type I membrane protein. Golgi apparatus. Cell surface
Tissue Location Expressed at a low level in a large number of cells of hematopoietic origin. Isoform 1 and isoform 2 are always found to be coexpressed
Research Areas
Citations (0)
citation

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References

1.Haematologica. 2015 Sep;100(9):e341-4.2.Blood. 2012 Jul 26;120(4):868-79.

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$ 385.00
Cat# AO2656a
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