Register or Login
All
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
COVID19
>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   GPCR Antibodies   >   GRM2   

GRM2

Purified Mouse Monoclonal Antibody

     
  • E - GRM2 AO2669a
    Figure 1:Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
    detail
  • WB - GRM2 AO2669a
    Figure 2:Western blot analysis using GRM2 mAb against human GRM2 (AA: extra 414-558) recombinant protein. (Expected MW is 42.4 kDa)
    detail
  • WB - GRM2 AO2669a
    Figure 4:Western blot analysis using GRM2 mAb against HEK293 (1) and GRM2 (AA: extra 414-558)-hIgGFc transfected HEK293 (2) cell lysate.
    detail
  • WB - GRM2 AO2669a
    Figure 4:Western blot analysis using GRM2 mouse mAb against SK-N-SH (1), Jurkat (2), and SW620 (3) cell lysate.
    detail
  • FCM - GRM2 AO2669a
    Figure 5:Flow cytometric analysis of SK-N-SH cells using GRM2 mouse mAb (green) and negative control (red).
    detail
  • SPECIFICATION
  • CITATIONS
  • PROTOCOLS
  • BACKGROUND
  • detail
Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC, ICC, E
Primary Accession Q14416
Reactivity Human
Host Mouse
Clonality Monoclonal
Clone Names 6E4F6
Isotype Mouse IgG1
Calculated MW 95.6kDa
Immunogen Purified recombinant fragment of human GRM2 (AA: extra 414-558) expressed in E. Coli.
Formulation Purified antibody in PBS with 0.05% sodium azide
Additional Information
Gene ID 2912
Other Names GLUR2; mGlu2; GPRC1B; MGLUR2
Dilution E~~ 1/10000
WB~~ 1/500 - 1/2000
FCM~~1/200 - 1/400
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGRM2 is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GRM2 (HGNC:4594)
Synonyms GPRC1B, MGLUR2
Function G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. May mediate suppression of neurotransmission or may be involved in synaptogenesis or synaptic stabilization.
Cellular Location Cell membrane; Multi-pass membrane protein. Synapse. Cell projection, dendrite
Tissue Location Detected in brain cortex (at protein level). Widely expressed in different regions of the adult brain as well as in fetal brain.
Research Areas
Citations (0)
citation

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abcepta antibody to
info@abcepta.com, and receive a free "I Love Antibodies" mug.

References

1.Br J Pharmacol. 2015 May;172(9):2383-96.2.Brain Res. 2009 Jan 16;1249:244-50.

FeedBack
Abcepta welcomes feedback from its customers.

If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at tech@abcepta.com.

$ 385.00
Cat# AO2669a
Size:
Quantity:
Availability: 7-10 days
Bulk Size

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abcepta, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions
"