|Application ||WB, IHC-P, E|
|Calculated MW||35399 Da|
|Antigen Region||111-138 aa|
|Other Names||Apolipoprotein F, Apo-F, Lipid transfer inhibitor protein, LTIP, APOF|
|Target/Specificity||This APOF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the Central region of human APOF.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||APOF Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Minor apolipoprotein that associates with LDL. Inhibits cholesteryl ester transfer protein (CETP) activity and appears to be an important regulator of cholesterol transport. Also associates to a lesser degree with VLDL, Apo-AI and Apo-AII.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene is one of the minor apolipoproteins found in plasma. This protein forms complexes with lipoproteins and may be involved in transport and/or esterification of cholesterol.
Ruano, G., et al. Pharmacogenomics 11(7):959-971(2010)
Mosbruger, T.L., et al. J. Infect. Dis. 201(9):1371-1380(2010)
Chen, S.N., et al. BMC Med. Genet. 10, 111 (2009) :
He, Y., et al. J. Lipid Res. 49(7):1529-1537(2008)
Morton, R.E., et al. J. Lipid Res. 49(1):127-135(2008)
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