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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CCNY Antibody (Center)   

CCNY Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CCNY Antibody (Center) AP10135C
    CCNY Antibody (Center) (Cat. #AP10135c) western blot analysis in mouse bladder tissue lysates (35ug/lane).This demonstrates the CCNY antibody detected the CCNY protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8ND76
Other Accession Q8BGU5, NP_659449.3, NP_859049.2
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 39337 Da
Antigen Region 140-169 aa
Additional Information
Gene ID 219771
Other Names Cyclin-Y, Cyc-Y, Cyclin box protein 1, Cyclin fold protein 1, cyclin-X, CCNY, C10orf9, CBCP1, CFP1
Target/Specificity This CCNY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-169 amino acids from the Central region of human CCNY.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCNY Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C10orf9, CBCP1, CFP1
Function Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Cellular Location Cell membrane; Lipid-anchor; Cytoplasmic side
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Cyclins, such as CCNY, control cell division cycles and regulate cyclin-dependent kinases (e.g., CDC2; MIM 116940) (Li et al., 2009 [PubMed 18060517]).


Wang, K., et al. Hum. Mol. Genet. 19(10):2059-2067(2010)
Xu, Y., et al. Oncol. Res. 18(8):359-364(2010)
Chapuis, J., et al. Mol. Psychiatry 14(11):1004-1016(2009)
Henckaerts, L., et al. Clin. Gastroenterol. Hepatol. 7(9):972-980(2009)
Jiang, M., et al. FEBS Lett. 583(13):2171-2178(2009)

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Cat# AP10135C
(40 western blots)
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