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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   FBXW12 Antibody (C-term)   

FBXW12 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FBXW12 Antibody (C-term) AP10268b
    FBXW12 Antibody (C-term) (Cat. #AP10268b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the FBXW12 antibody detected the FBXW12 protein (arrow).
  • IHC-P - FBXW12 Antibody (C-term) AP10268b
    FBXW12 antibody(C-term) (Cat. #AP10268b) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the FBXW12 antibody(C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - FBXW12 Antibody (C-term) AP10268b
    FBXW12 Antibody (C-term) (Cat. #AP10268b) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q6X9E4
Other Accession NP_001153399.1, NP_001153401.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53056 Da
Antigen Region 291-320 aa
Additional Information
Gene ID 285231
Other Names F-box/WD repeat-containing protein 12, F-box and WD-40 domain-containing protein 12, F-box only protein 35, FBXW12, FBW12, FBXO12, FBXO35
Target/Specificity This FBXW12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 291-320 amino acids from the C-terminal region of human FBXW12.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFBXW12 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXW12
Synonyms FBW12, FBXO12, FBXO35
Function Substrate-recognition component of the SCF (SKP1-CUL1-F- box protein)-type E3 ubiquitin ligase complex.
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].


Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
Zeng, L., et al. Mol. Biol. Rep. 31(1):51-57(2004)

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$ 295.00
$ 99.00
Cat# AP10268b
(40 western blots)
Availability: In Stock
Bulk Size
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