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>   home   >   Products   >   Primary Antibodies   >   Cardiovascular   >   PEAR1 Antibody (C-term)   

PEAR1 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PEAR1 Antibody (C-term) AP10334B
    PEAR1 Antibody (C-term) (Cat. #AP10334b) western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the PEAR1 antibody detected the PEAR1 protein (arrow).
  • IHC-P - PEAR1 Antibody (C-term) AP10334B
    PEAR1 antibody (C-term) (Cat. #AP10334b) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the PEAR1 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5VY43
Other Accession NP_001073940.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 110666 Da
Antigen Region 961-990 aa
Additional Information
Gene ID 375033
Other Names Platelet endothelial aggregation receptor 1, hPEAR1, Multiple epidermal growth factor-like domains protein 12, Multiple EGF-like domains protein 12, PEAR1, MEGF12
Target/Specificity This PEAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 961-990 amino acids from the C-terminal region of human PEAR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPEAR1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PEAR1
Synonyms MEGF12
Function When overexpressed, reduces the number of both early and late non-adherent myeloid progenitor cells.
Cellular Location Cell membrane; Single-pass membrane protein. Note=Detected on the cell surface in resting platelets.
Tissue Location Expressed in umbilical vein endothelial cells and platelets (at protein level). Expressed in heart, kidney, skeletal muscle, pancreas, ovary, breast, lung, brain cortex, hypothalamus, spinal cord, dorsal root ganglion, endothelial cells of umbilical cord artery and vein, megakaryocytes, osteoblasts, coronary muscle and erythroid cells. Weakly expressed in peripheral blood leukocytes and macrophages
Research Areas
Citations (0)

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PEAR1 is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation (Nanda et al., 2005 [PubMed 15851471]).


Johnson, A.D., et al. Nat. Genet. 42(7):608-613(2010)
Jones, C.I., et al. Blood 114(7):1405-1416(2009)
Herrera-Galeano, J.E., et al. Arterioscler. Thromb. Vasc. Biol. 28(8):1484-1490(2008)
Nanda, N., et al. J. Biol. Chem. 280(26):24680-24689(2005)
Nanda, N., et al. J. Biol. Chem. 280(26):24680-24689(2005)

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$ 295.00
$ 99.00
Cat# AP10334B
(40 western blots)
Availability: In Stock
Bulk Size
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