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ATPBD3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ATPBD3 Antibody (Center) AP10349C
    ATPBD3 Antibody (Center) (Cat. #AP10349c) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the ATPBD3 antibody detected the ATPBD3 protein (arrow).
  • IHC-P - ATPBD3 Antibody (Center) AP10349C
    ATPBD3 antibody (Center) (Cat. #AP10349c) immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ATPBD3 antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q7Z7A3
Other Accession Q0VC66, NP_660275.2
Reactivity Human, Mouse
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 36450 Da
Antigen Region 208-236 aa
Additional Information
Gene ID 90353
Other Names Cytoplasmic tRNA 2-thiolation protein 1 {ECO:0000255|HAMAP-Rule:MF_03053}, 277- {ECO:0000255|HAMAP-Rule:MF_03053}, ATP-binding domain-containing protein 3 {ECO:0000255|HAMAP-Rule:MF_03053}, Cancer-associated gene protein, Cytoplasmic tRNA adenylyltransferase 1 {ECO:0000255|HAMAP-Rule:MF_03053}, CTU1 {ECO:0000255|HAMAP-Rule:MF_03053}
Target/Specificity This ATPBD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 208-236 amino acids from the Central region of human ATPBD3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsATPBD3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CTU1 {ECO:0000255|HAMAP-Rule:MF_03053}
Function Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Cellular Location Cytoplasm.
Research Areas
Citations (0)

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Schlieker, C.D., et al. Proc. Natl. Acad. Sci. U.S.A. 105(47):18255-18260(2008)
Beausoleil, S.A., et al. Nat. Biotechnol. 24(10):1285-1292(2006)

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Cat# AP10349C
(40 western blots)
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