|Application ||WB, FC, E|
|Calculated MW||25498 Da|
|Antigen Region||33-61 aa|
|Other Names||Transmembrane protein 65, TMEM65|
|Target/Specificity||This TMEM65 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 amino acids from the N-terminal region of human TMEM65.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TMEM65 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in cardiac development and function. Regulates cardiac conduction and the function of the gap junction protein GJA1. Contributes to the stability and proper localization of GJA1 to cardiac intercalated disk thereby regulating gap junction communication.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Note=Localizes at the intercalated disk in the ventricular tissue|
|Tissue Location||Predominantly expressed the ventricular tissue (at protein level).|
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Provided below are standard protocols that you may find useful for product applications.
Gerhard, D.S., et al. Genome Res. 14 (10B), 2121-2127 (2004) :
Bonaldo, M.F., et al. Genome Res. 6(9):791-806(1996)
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