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CCDC19 Antibody (N-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CCDC19 Antibody (N-term) AP10437a
    CCDC19 Antibody (N-term) (Cat. #AP10437a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the CCDC19 antibody detected the CCDC19 protein (arrow).
    detail
  • IHC-P - CCDC19 Antibody (N-term) AP10437a
    CCDC19 Antibody (N-term) (Cat. #AP10437a) immunohistochemistry analysis in formalin fixed and paraffin embedded human testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the CCDC19 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession Q9UL16
Other Accession NP_036469.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 65730 Da
Antigen Region 106-135 aa
Additional Information
Gene ID 25790
Other Names Protein CFAP45, mitochondrial, Cilia- and flagella-associated protein 45 {ECO:0000312|HGNC:HGNC:17229}, Coiled-coil domain-containing protein 19, Nasopharyngeal epithelium-specific protein 1 {ECO:0000312|EMBL:AAD558171}, CFAP45 (HGNC:17229)
Target/Specificity This CCDC19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the N-terminal region of human CCDC19.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCCDC19 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CFAP45 (HGNC:17229)
Function Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189). It is an AMP-binding protein that may facilitate dynein ATPase-dependent ciliary and flagellar beating via adenine nucleotide homeostasis. May function as a donor of AMP to AK8 and hence promote ADP production (PubMed:33139725).
Cellular Location Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme Note=Located in the proximal region of respiratory cilia
Tissue Location Expressed in respiratory cells and in sperm (at protein level) (PubMed:33139725). Expressed in nasopharyngeal epithelium and trachea (PubMed:10524255).
Research Areas
Citations (0)
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References

Li, Z., et al. Gene 237(1):235-240(1999)

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$ 182.50
$ 70.00
Cat# AP10437a
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