CCDC19 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC-P, E |
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Primary Accession | Q9UL16 |
Other Accession | NP_036469.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 65730 Da |
Antigen Region | 106-135 aa |
Gene ID | 25790 |
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Other Names | Protein CFAP45, mitochondrial, Cilia- and flagella-associated protein 45 {ECO:0000312|HGNC:HGNC:17229}, Coiled-coil domain-containing protein 19, Nasopharyngeal epithelium-specific protein 1 {ECO:0000312|EMBL:AAD558171}, CFAP45 (HGNC:17229) |
Target/Specificity | This CCDC19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 106-135 amino acids from the N-terminal region of human CCDC19. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CCDC19 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CFAP45 (HGNC:17229) |
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Function | Microtubule inner protein (MIP) part of the dynein-decorated doublet microtubules (DMTs) in cilia axoneme, which is required for motile cilia beating (PubMed:36191189). It is an AMP-binding protein that may facilitate dynein ATPase-dependent ciliary and flagellar beating via adenine nucleotide homeostasis. May function as a donor of AMP to AK8 and hence promote ADP production (PubMed:33139725). |
Cellular Location | Cytoplasm, cytoskeleton, cilium axoneme. Cytoplasm, cytoskeleton, flagellum axoneme Note=Located in the proximal region of respiratory cilia |
Tissue Location | Expressed in respiratory cells and in sperm (at protein level) (PubMed:33139725). Expressed in nasopharyngeal epithelium and trachea (PubMed:10524255). |
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Provided below are standard protocols that you may find useful for product applications.
References
Li, Z., et al. Gene 237(1):235-240(1999)
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