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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   ITGAE Antibody (C-term)   

ITGAE Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ITGAE Antibody (C-term) AP10494b
    ITGAE Antibody (C-term) (Cat. #AP10494b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the ITGAE antibody detected the ITGAE protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P38570
Other Accession NP_002199.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 130159 Da
Antigen Region 1146-1173 aa
Additional Information
Gene ID 3682
Other Names Integrin alpha-E, HML-1 antigen, Integrin alpha-IEL, Mucosal lymphocyte 1 antigen, CD103, Integrin alpha-E light chain, Integrin alpha-E heavy chain, ITGAE
Target/Specificity This ITGAE antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1146-1173 amino acids from the C-terminal region of human ITGAE.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsITGAE Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Integrin alpha-E/beta-7 is a receptor for E-cadherin. It mediates adhesion of intra-epithelial T-lymphocytes to epithelial cell monolayers.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed on a subclass of T-lymphocytes known as intra-epithelial lymphocytes which are located between mucosal epithelial cells
Research Areas
Citations (0)

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Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. ITGAE encodes an I-domain-containing alpha integrin that undergoes post-translational cleavage in the extracellular domain, yielding disulfide-linked heavy and light chains. In combination with the beta 7 integrin, this protein forms the E-cadherin binding integrin known as the human mucosal lymphocyte-1 antigen. This protein is preferentially expressed in human intestinal intraepithelial lymphocytes (IEL), and in addition to a role in adhesion, it may serve as an accessory molecule for IEL activation. [provided by RefSeq].


Silva, L.K., et al. Eur. J. Hum. Genet. 18(11):1221-1227(2010)
Liu, Y.H., et al. Ophthalmology 117(8):1645-1651(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Heron, M., et al. Clin. Immunol. 133(1):117-125(2009)

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$ 295.00
$ 99.00
Cat# AP10494b
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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