|Application ||WB, FC, E|
|Calculated MW||27863 Da|
|Antigen Region||186-215 aa|
|Other Names||Receptor-transporting protein 4, 28 kDa interferon-responsive protein, RTP4, IFRG28|
|Target/Specificity||This RTP4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-215 amino acids from the C-terminal region of human RTP4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RTP4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Probable chaperone protein which facilitates trafficking and functional cell surface expression of some G-protein coupled receptors (GPCRs). Promotes functional expression of the bitter taste receptor TAS2R16 (PubMed:16720576). Also promotes functional expression of the opioid receptor heterodimer OPRD1-OPRM1 (By similarity).|
|Cellular Location||Membrane; Single-pass type III membrane protein|
|Tissue Location||Expressed in circumvallate papillae and testis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
RTP4 belongs to the TMEM7 family. The function of this protein remains unknown.
Behrens, M., et al. J. Biol. Chem. 281(29):20650-20659(2006)
Clark, A.J., et al. Trends Endocrinol. Metab. 16(10):451-457(2005)
Saito, H., et al. Cell 119(5):679-691(2004)
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