|Application ||WB, IHC-P, E|
|Calculated MW||13821 Da|
|Antigen Region||62-90 aa|
|Other Names||Lymphocyte antigen 6 complex locus protein G6c, LY6G6C, C6orf24, G6C, NG24|
|Target/Specificity||This LY6G6C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-90 amino acids from the C-terminal region of human LY6G6C.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LY6G6C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C6orf24, G6C, NG24|
|Cellular Location||Cell membrane; Lipid-anchor, GPI-anchor|
|Tissue Location||Highly expressed at the leading edges of cells, on filopodia.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Barcellos, L.F., et al. PLoS Genet. 5 (10), E1000696 (2009) :
Xie, T., et al. Genome Res. 13(12):2621-2636(2003)
Mallya, M., et al. Genomics 80(1):113-123(2002)
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