ATPGD1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P, WB, E |
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Primary Accession | A5YM72 |
Other Accession | NP_065862.1, NP_001159694.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 88484 Da |
Antigen Region | 239-268 aa |
Gene ID | 57571 |
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Other Names | Carnosine synthase 1, ATP-grasp domain-containing protein 1, CARNS1, ATPGD1, KIAA1394 |
Target/Specificity | This ATPGD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the N-terminal region of human ATPGD1. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ATPGD1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CARNS1 (HGNC:29268) |
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Synonyms | ATPGD1, KIAA1394 |
Function | Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine. |
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Provided below are standard protocols that you may find useful for product applications.
Background
CARNS1 (EC 6.3.2.11), a member of the ATP-grasp family of ATPases, catalyzes the formation of carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyryl-L-histidine), which are found mainly in skeletal muscle and the central nervous system, respectively (Drozak et al., 2010 [PubMed 20097752]).
References
Drozak, J., et al. J. Biol. Chem. 285(13):9346-9356(2010)
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