|Application ||WB, IHC-P, E|
|Other Accession||NP_065862.1, NP_001159694.1|
|Calculated MW||88484 Da|
|Antigen Region||239-268 aa|
|Other Names||Carnosine synthase 1, ATP-grasp domain-containing protein 1, CARNS1, ATPGD1, KIAA1394|
|Target/Specificity||This ATPGD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 239-268 amino acids from the N-terminal region of human ATPGD1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ATPGD1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the synthesis of carnosine and homocarnosine. Carnosine is synthesized more efficiently than homocarnosine.|
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Provided below are standard protocols that you may find useful for product applications.
CARNS1 (EC 188.8.131.52), a member of the ATP-grasp family of ATPases, catalyzes the formation of carnosine (beta-alanyl-L-histidine) and homocarnosine (gamma-aminobutyryl-L-histidine), which are found mainly in skeletal muscle and the central nervous system, respectively (Drozak et al., 2010 [PubMed 20097752]).
Drozak, J., et al. J. Biol. Chem. 285(13):9346-9356(2010)
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