CD37 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, E |
---|---|
Primary Accession | P11049 |
Other Accession | NP_001765.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 31703 Da |
Antigen Region | 101-130 aa |
Gene ID | 951 |
---|---|
Other Names | Leukocyte antigen CD37, Tetraspanin-26, Tspan-26, CD37, CD37, TSPAN26 |
Target/Specificity | This CD37 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the Central region of human CD37. |
Dilution | WB~~1:1000 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CD37 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CD37 |
---|---|
Synonyms | TSPAN26 |
Cellular Location | Membrane; Multi-pass membrane protein. |
Tissue Location | B-lymphocytes. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It may play a role in T-cell-B-cell interactions. Alternate splicing results in multiple transcript variants encoding different isoforms.
References
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Gartlan, K.H., et al. J. Immunol. 185(6):3158-3166(2010)
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Zhao, X., et al. Blood 110(7):2569-2577(2007)
Meyer-Wentrup, F., et al. J. Immunol. 178(1):154-162(2007)
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