ENTPD3 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, FC, IHC-P, E |
---|---|
Primary Accession | O75355 |
Other Accession | NP_001239.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 59105 Da |
Antigen Region | 496-527 aa |
Gene ID | 956 |
---|---|
Other Names | Ectonucleoside triphosphate diphosphohydrolase 3, NTPDase 3, CD39 antigen-like 3, Ecto-ATP diphosphohydrolase 3, Ecto-ATPDase 3, Ecto-ATPase 3, Ecto-apyrase 3, HB6, ENTPD3, CD39L3 |
Target/Specificity | This ENTPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-527 amino acids from the C-terminal region of human ENTPD3. |
Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ENTPD3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ENTPD3 |
---|---|
Synonyms | CD39L3 {ECO:0000303|PubMed:9676430} |
Function | Has a threefold preference for the hydrolysis of ATP over ADP. |
Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q8BFW6}; Multi-pass membrane protein |
Tissue Location | Expressed in adult brain, pancreas, spleen and prostate (PubMed:9676430). Moderate or low expression is seen in most tissues (PubMed:9676430). Not expressed in liver and peripheral blood leukocytes (PubMed:9676430). |
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Provided below are standard protocols that you may find useful for product applications.
Background
ENTPD3 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD3 contains 4 apyrase-conserved regions which is characteristic of NTPases.
References
Fausther, M., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 298 (6), L804-L818 (2010) :
Gaddie, K.J., et al. Biochemistry 48(40):9437-9447(2009)
Munkonda, M.N., et al. FEBS J. 276(2):479-496(2009)
Munkonda, M.N., et al. Biochem. Pharmacol. 74(10):1524-1534(2007)
Ivanenkov, V.V., et al. Biochemistry 44(25):8998-9012(2005)
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