|Application ||WB, IHC-P, FC, E|
|Calculated MW||59105 Da|
|Antigen Region||496-527 aa|
|Other Names||Ectonucleoside triphosphate diphosphohydrolase 3, NTPDase 3, CD39 antigen-like 3, Ecto-ATP diphosphohydrolase 3, Ecto-ATPDase 3, Ecto-ATPase 3, Ecto-apyrase 3, HB6, ENTPD3, CD39L3|
|Target/Specificity||This ENTPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 496-527 amino acids from the C-terminal region of human ENTPD3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ENTPD3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has a threefold preference for the hydrolysis of ATP over ADP.|
|Cellular Location||Membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in adult brain, pancreas, spleen and prostate. Moderate or low expression is seen in most tissues. Not expressed in liver and peripheral blood leukocytes|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
ENTPD3 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD3 contains 4 apyrase-conserved regions which is characteristic of NTPases.
Fausther, M., et al. Am. J. Physiol. Lung Cell Mol. Physiol. 298 (6), L804-L818 (2010) :
Gaddie, K.J., et al. Biochemistry 48(40):9437-9447(2009)
Munkonda, M.N., et al. FEBS J. 276(2):479-496(2009)
Munkonda, M.N., et al. Biochem. Pharmacol. 74(10):1524-1534(2007)
Ivanenkov, V.V., et al. Biochemistry 44(25):8998-9012(2005)
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