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PRSS1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PRSS1 Antibody (Center) AP10735c
    PRSS1 Antibody (Center) (Cat. #AP10735c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PRSS1 antibody detected the PRSS1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P07477
Other Accession NP_002760.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 26558 Da
Antigen Region 81-107 aa
Additional Information
Gene ID 5644
Other Names Trypsin-1, Beta-trypsin, Cationic trypsinogen, Serine protease 1, Trypsin I, Alpha-trypsin chain 1, Alpha-trypsin chain 2, PRSS1, TRP1, TRY1, TRYP1
Target/Specificity This PRSS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-107 amino acids from the Central region of human PRSS1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRSS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRSS1
Synonyms TRP1, TRY1, TRYP1
Function Has activity against the synthetic substrates Boc-Phe- Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val- Pro-Arg-Mec. The single-chain form is more active than the two- chain form against all of these substrates.
Cellular Location Secreted, extracellular space.
Research Areas
Citations (0)

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This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is secreted by the pancreas and cleaved to its active form in the small intestine. It is active on peptide linkages involving the carboxyl group of lysine or arginine. Mutations in this gene are associated with hereditary pancreatitis. This gene and several other trypsinogen genes are localized to the T cell receptor beta locus on chromosome 7.


Joergensen, M.T., et al. Am. J. Gastroenterol. 105(8):1876-1883(2010)
Gasiorowska, A., et al. Dig. Dis. Sci. (2010) In press :
Szmola, R., et al. J. Med. Genet. 47(5):348-350(2010)
Nakanuma, S., et al. Int. J. Oncol. 36(4):793-800(2010)
Johansen, D., et al. Pancreatology 10 (2-3), 229-237 (2010) :

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Cat# AP10735c
(40 western blots)
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