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SERPINA6 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, IF, WB, E |
|---|---|
| Primary Accession | P08185 |
| Other Accession | NP_001747.2 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 45141 Da |
| Antigen Region | 197-225 aa |
| Gene ID | 866 |
|---|---|
| Other Names | Corticosteroid-binding globulin, CBG, Serpin A6, Transcortin, SERPINA6, CBG |
| Target/Specificity | This SERPINA6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-225 amino acids from the Central region of human SERPINA6. |
| Dilution | IF~~1:10~50 WB~~1:1000 IHC-P~~1:100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SERPINA6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SERPINA6 |
|---|---|
| Synonyms | CBG |
| Function | Major transport protein for glucocorticoids and progestins in the blood of almost all vertebrate species. |
| Cellular Location | Secreted. |
| Tissue Location | Plasma; synthesized in liver. Has also been identified in a number of glycocorticoid responsive cells |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.
References
Bailey, S.D., et al. Diabetes Care (2010) In press :
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Holliday, K.L., et al. J Psychosom Res 68(5):469-474(2010)
Braun, B.C., et al. J. Steroid Biochem. Mol. Biol. 120(1):30-37(2010)
Lewis, J.G., et al. Horm. Metab. Res. 42(4):274-279(2010)
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