|Application ||IHC-P, WB, E|
|Other Accession||Q62381, NP_036596.3|
|Calculated MW||114709 Da|
|Antigen Region||874-901 aa|
|Other Names||Tolloid-like protein 1, 3424-, TLL1, TLL|
|Target/Specificity||This TLL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 874-901 amino acids from the C-terminal region of human TLL1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TLL1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Protease which processes procollagen C-propeptides, such as chordin, pro-biglycan and pro-lysyl oxidase. Required for the embryonic development. Predominant protease, which in the development, influences dorsal-ventral patterning and skeletogenesis.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes an astacin-like zinc-dependent metalloprotease and is a subfamily member of the metzincin family. A similar protein in mice is required during heart development and specifically processes procollagen C-propeptides and chordin at similar cleavage sites.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Berry, R., et al. FEBS Lett. 584(4):657-661(2010)
Sabirzhanova, I.B., et al. Biochem. Biophys. Res. Commun. 389(2):338-342(2009)
Stanczak, P., et al. Eur. J. Hum. Genet. 17(3):344-351(2009)
Mac Sweeney, A., et al. J. Mol. Biol. 384(1):228-239(2008)
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