|Application ||WB, E|
|Calculated MW||7965 Da|
|Antigen Region||48-72 aa|
|Other Names||Small proline-rich protein 2A, SPR-2A, 2-1, SPRR2A|
|Target/Specificity||This SPRR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-72 amino acids from the C-terminal region of human SPRR2A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SPRR2A Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.|
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Provided below are standard protocols that you may find useful for product applications.
Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane.
Kainu, K., et al. Exp. Dermatol. 18(2):109-115(2009)
Demetris, A.J., et al. J. Hepatol. 48(2):276-288(2008)
Tong, L., et al. Invest. Ophthalmol. Vis. Sci. 47(5):1938-1946(2006)
Hong, S.H., et al. Mol. Cells 17(3):477-484(2004)
Cabral, A., et al. J. Biol. Chem. 278(20):17792-17799(2003)
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