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ZC4H2 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q9NQZ6 |
| Other Accession | Q68FG0, NP_061154.1 |
| Reactivity | Human |
| Predicted | Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 26244 Da |
| Antigen Region | 196-224 aa |
| Gene ID | 55906 |
|---|---|
| Other Names | Zinc finger C4H2 domain-containing protein, Hepatocellular carcinoma-associated antigen 127, ZC4H2, HCA127, KIAA1166 |
| Target/Specificity | This ZC4H2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 196-224 amino acids from the C-terminal region of human ZC4H2. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ZC4H2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | ZC4H2 |
|---|---|
| Synonyms | HCA127, KIAA1166 |
| Function | Plays a role in interneurons differentiation (PubMed:26056227). Involved in neuronal development and in neuromuscular junction formation. |
| Cellular Location | Cytoplasm. Nucleus Postsynaptic cell membrane. Note=Upon transfection into mouse primary hippocampal neurons, localizes at excitatory, but not inhibitory, postsynaptic sites |
| Tissue Location | Expressed in fetal tissues, including in brain, intestine, lung, kidney and muscle (PubMed:23623388). Isoform 1 is expressed in numerous fetal brain regions. Isoform 3 is highly expressed in numerous fetal brain regions and spinal cord (PubMed:26056227). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
This protein contains a C4H2-type zinc finger and is thought to be involved in zinc ion binding. There are 3 isoforms produced by alternative splicing.
References
Wu, C., et al. Proteomics 7(11):1775-1785(2007)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Wang, Y., et al. J. Immunol. 169(2):1102-1109(2002)
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