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OAZ2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - OAZ2 Antibody (C-term) AP10765b
    OAZ2 Antibody (C-term) (Cat. #AP10765b) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the OAZ2 antibody detected the OAZ2 protein (arrow).
  • IHC-P - OAZ2 Antibody (C-term) AP10765b
    OAZ2 antibody (C-term) (Cat. #AP10765b) immunohistochemistry analysis in formalin fixed and paraffin embedded human skin carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the OAZ2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95190
Other Accession O08608, NP_002528.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 21011 Da
Antigen Region 125-151 aa
Additional Information
Gene ID 4947
Other Names Ornithine decarboxylase antizyme 2, AZ2, ODC-Az 2, OAZ2
Target/Specificity This OAZ2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-151 amino acids from the C-terminal region of human OAZ2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOAZ2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OAZ2
Function Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake by binding to ODC1 without promoting its degradation (PubMed:17900240). Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol.
Cellular Location Nucleus.
Research Areas
Citations (0)

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Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation. [provided by RefSeq].


Geerts, D., et al. Int. J. Cancer 126(9):2012-2024(2010)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Mangold, U., et al. Biochem. J. 385 (PT 1), 21-28 (2005) :
Chen, H., et al. J. Biol. Chem. 277(48):45957-45961(2002)
Coffino, P. Proc. Natl. Acad. Sci. U.S.A. 97(9):4421-4423(2000)

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Cat# AP10765b
(40 western blots)
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