|Application ||WB, IHC-P, FC, E|
|Calculated MW||21628 Da|
|Antigen Region||6-35 aa|
|Other Names||Protein Hikeshi, C11orf73|
|Target/Specificity||This CK073 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 6-35 amino acids from the N-terminal region of human CK073.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CK073 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a specific nuclear import carrier for HSP70 proteins following heat-shock stress: acts by mediating the nucleoporin-dependent translocation of ATP-bound HSP70 proteins into the nucleus. HSP70 proteins import is required to protect cells from heat shock damages. Does not translocate ADP-bound HSP70 proteins into the nucleus.|
|Cellular Location||Cytoplasm, cytosol. Nucleus|
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Provided below are standard protocols that you may find useful for product applications.
Required for organization and/or function of the secretory apparatus in Clara cells in lung (By similarity).
Need, A.C., et al. Hum. Mol. Genet. 18(23):4650-4661(2009)
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