MCAR1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q9H1U9 |
Other Accession | NP_219480.1 |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 33672 Da |
Antigen Region | 46-75 aa |
Gene ID | 92014 |
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Other Names | Solute carrier family 25 member 51, Mitochondrial carrier triple repeat protein 1, SLC25A51, MCART1 |
Target/Specificity | This MCAR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the N-terminal region of human MCAR1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MCAR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SLC25A51 {ECO:0000303|PubMed:32906142, ECO:0000312|HGNC:HGNC:23323} |
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Function | Mitochondrial membrane carrier protein that mediates the import of NAD(+) into mitochondria (PubMed:32906142, PubMed:33262325, PubMed:33087354). Mitochondrial NAD(+) is required for glycolysis and mitochondrial respiration (PubMed:32906142, PubMed:33262325, PubMed:33087354). Compared to SLC25A52, SLC25A51-mediated transport is essential for the import of NAD(+) in mitochondria (PubMed:32906142). The transport mechanism, uniport or antiport, its electrogenicity and substrate selectivity, remain to be elucidated. |
Cellular Location | Mitochondrion inner membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
References
Humphray, S.J., et al. Nature 429(6990):369-374(2004)
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