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CO027 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| FC, WB, E |
|---|---|
| Primary Accession | Q2M3C6 |
| Other Accession | Q9N0B5, NP_689548.2 |
| Reactivity | Human, Mouse |
| Predicted | Monkey |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 58444 Da |
| Antigen Region | 503-531 aa |
| Gene ID | 123591 |
|---|---|
| Other Names | Transmembrane protein C15orf27, C15orf27 |
| Target/Specificity | This CO027 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 503-531 amino acids from the C-terminal region of human CO027. |
| Dilution | WB~~1:1000 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CO027 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TMEM266 (HGNC:26763) |
|---|---|
| Function | Voltage-sensor protein present on the post-synaptic side of glutamatergic mossy fibers and granule cells in the cerebellum (PubMed:25165868, PubMed:30810529). Despite the presence of a voltage- sensor segment, does not form a functional ion channel and its precise role remains unclear (PubMed:25165868, PubMed:30810529). Undergoes both rapid and slow structural rearrangements in response to changes in voltage (PubMed:30810529). Contains a zinc-binding site that can regulate the slow conformational transition (PubMed:30810529). |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Cell projection, dendrite Perikaryon. Note=Present in the dendrites and soma of cerebellar granule neurons, but not in their axon |
| Tissue Location | Mainly expressed in the cerebellum (PubMed:25165868). Also expressed in cerebral cortex, skeletal muscle and thyroid, but at much lower levels (PubMed:25165868) |
Research Areas
Citations (0)
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Zody, M.C., et al. Nature 440(7084):671-675(2006)
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$ 365.00
$ 140.00
Cat# AP10811b
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