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LARP6 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LARP6 Antibody  (N-term) AP10830A
    LARP6 Antibody (N-term) (Cat. #AP10830a) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the LARP6 antibody detected the LARP6 protein (arrow).
  • IHC-P - LARP6 Antibody  (N-term) AP10830A
    LARP6 antibody (N-term) (Cat. #AP10830a) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the LARP6 antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - LARP6 Antibody  (N-term) AP10830A
    LARP6 Antibody (N-term) (Cat. #AP10830a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BRS8
Other Accession NP_060827.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54737 Da
Antigen Region 7-35 aa
Additional Information
Gene ID 55323
Other Names La-related protein 6, Acheron, Achn, La ribonucleoprotein domain family member 6, LARP6
Target/Specificity This LARP6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-35 amino acids from the N-terminal region of human LARP6.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLARP6 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LARP6
Function Regulates the coordinated translation of type I collagen alpha-1 and alpha-2 mRNAs, CO1A1 and CO1A2. Stabilizes mRNAs through high-affinity binding of a stem-loop structure in their 5' UTR. This regulation requires VIM and MYH10 filaments, and the helicase DHX9.
Cellular Location Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the cytoplasm
Tissue Location Expressed in numerous tissues.
Citations (0)

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LARP6 is a member of the La ribonucleoprotein domain family, which all contain one characteristic La motif. LARP6 shuttles between the cytoplasm and nucleus. It is proposed that members of this family play a role in translation and mRNA stability.


Cai, L., et al. J. Mol. Biol. 395(2):309-326(2010)
Glenn, H.L., et al. Am. J. Physiol., Cell Physiol. 298 (1), C46-C55 (2010) :
Valavanis, C., et al. Gene 393 (1-2), 101-109 (2007) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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Cat# AP10830A
(40 western blots)
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