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DPY19L1 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| FC, IHC-P, WB, E |
|---|---|
| Primary Accession | Q2PZI1 |
| Other Accession | A6X919, NP_056098.1, D4AD75 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 77319 Da |
| Antigen Region | 557-586 aa |
| Gene ID | 23333 |
|---|---|
| Other Names | Probable C-mannosyltransferase DPY19L1, 241-, Dpy-19-like protein 1, Protein dpy-19 homolog 1, DPY19L1, GA0500, KIAA0877 |
| Target/Specificity | This DPY19L1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 557-586 amino acids from the C-terminal region of human DPY19L1. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | DPY19L1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | DPY19L1 |
|---|---|
| Synonyms | GA0500, KIAA0877 |
| Function | C-mannosyltransferase that mediates the C-mannosylation tryptophan residues on target proteins. The reaction occurs on the luminal side of the endoplasmic reticulum and involves the transfer of a mannose unit from a dolichylphosphate mannose (Dol-P-Man) donor to an acceptor protein containing a WxxW consensus sequence (By similarity). C-mannosylates the first two tryptophans in the WxxWxxWxxC motif in thrombospondin (TSP) type-1 of UNC5A (By similarity). Regulates neurite extension during development (By similarity). |
| Cellular Location | Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:A6X919}; Multi-pass membrane protein |
| Tissue Location | Widely expressed.. |
Research Areas
Citations ( 0 )
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the DPY19 family. There are two named isoforms. The specific function of DPY19L1 is not yet known.
References
Strausberg, R.L., et al. Proc. Natl. Acad. Sci. U.S.A. 99(26):16899-16903(2002)
Nagase, T., et al. DNA Res. 5(6):355-364(1998)
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Discontinued
Cat# AP10859b
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