|Application ||WB, E|
|Calculated MW||35117 Da|
|Antigen Region||245-273 aa|
|Other Names||Olfactory receptor 10A4, HP2, Olfactory receptor-like protein JCG5, OR10A4, OR10A4P|
|Target/Specificity||This OR10A4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 245-273 amino acids from the C-terminal region of human OR10A4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OR10A4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Odorant receptor (Potential). May be involved in taste perception.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in the tongue.|
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Provided below are standard protocols that you may find useful for product applications.
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
Malnic, B., et al. Proc. Natl. Acad. Sci. U.S.A. 101(8):2584-2589(2004)
Fuchs, T., et al. Genomics 80(3):295-302(2002)
Gaudin, J.C., et al. Chem. Senses 26(9):1157-1166(2001)
Lane, R.P., et al. Proc. Natl. Acad. Sci. U.S.A. 98(13):7390-7395(2001)
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