|Application ||WB, IHC-P, FC, E|
|Calculated MW||47791 Da|
|Antigen Region||48-76 aa|
|Other Names||Monocarboxylate transporter 11, MCT 11, Solute carrier family 16 member 11, SLC16A11, MCT11|
|Target/Specificity||This SLC16A11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the N-terminal region of human SLC16A11.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC16A11 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Proton-linked monocarboxylate transporter. May catalyze the transport of monocarboxylates across the plasma membrane (Probable). Probably involved in hepatic lipid metabolism: overexpression results in an increase of triacylglycerol(TAG) levels, small increases in intracellular diacylglycerols and decreases in lysophosphatidylcholine, cholesterol ester and sphingomyelin lipids.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in liver, salivary gland and thyroid.|
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Provided below are standard protocols that you may find useful for product applications.
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).
Halestrap, A.P., et al. Pflugers Arch. 447(5):619-628(2004)
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