|Application ||WB, E|
|Other Accession||O02756, NP_005186.2, Q9N0J3|
|Calculated MW||28467 Da|
|Antigen Region||10-39 aa|
|Other Names||CCAAT/enhancer-binding protein delta, C/EBP delta, Nuclear factor NF-IL6-beta, NF-IL6-beta, CEBPD|
|Target/Specificity||This CEBPD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human CEBPD.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CEBPD Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||C/EBP is a DNA-binding protein that recognizes two different motifs: the CCAAT homology common to many promoters and the enhanced core homology common to many enhancers. Important transcriptional activator in the regulation of genes involved in immune and inflammatory responses, may play an important role in the regulation of the several genes associated with activation and/or differentiation of macrophages.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related protein CEBP-alpha. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses, and may be involved in the regulation of genes associated with activation and/or differentiation of macrophages. The cytogenetic location of this locus has been reported as both 8p11 and 8q11.
Zannetti, C., et al. J. Biol. Chem. 285(45):34773-34780(2010)
Wang, J., et al. Proc. Natl. Acad. Sci. U.S.A. 107(37):16131-16136(2010)
Hour, T.C., et al. Biochem. Pharmacol. 80(3):325-334(2010)
Bennett, C.E., et al. Diab Vasc Dis Res 7(3):195-203(2010)
Payne, V.A., et al. Biochem. J. 425(1):215-223(2010)
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