|Application ||WB, E|
|Other Accession||P26801, P53568, Q3T0B9, NP_001797.1|
|Calculated MW||16408 Da|
|Antigen Region||83-110 aa|
|Other Names||CCAAT/enhancer-binding protein gamma, C/EBP gamma, CEBPG|
|Target/Specificity||This CEBPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 83-110 amino acids from the C-terminal region of human CEBPG.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CEBPG Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds to the enhancer element PRE-I (positive regulatory element-I) of the IL-4 gene. Might change the DNA-binding specificity of other transcription factors and recruit them to unusual DNA sites.|
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Provided below are standard protocols that you may find useful for product applications.
The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements.
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Crawford, E.L., et al. Carcinogenesis 28(12):2552-2559(2007)
Mullins, D.N., et al. BMC Cancer 5, 141 (2005) :
Newman, J.R., et al. Science 300(5628):2097-2101(2003)
Hattori, T., et al. Oncogene 22(9):1273-1280(2003)
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