|Application ||WB, E|
|Other Accession||Q5XH61, Q9CXE2, Q5XFY4, NP_001019979.1, NP_066273.1|
|Predicted||Zebrafish, Mouse, Xenopus|
|Calculated MW||22810 Da|
|Antigen Region||1-30 aa|
|Other Names||B-cell CLL/lymphoma 7 protein family member A, BCL7A|
|Target/Specificity||This BCL7A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human BCL7A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BCL7A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene is directly involved, with Myc and IgH, in a three-way gene translocation in a Burkitt lymphoma cell line. As a result of the gene translocation, the N-terminal region of the gene product is disrupted, which is thought to be related to the pathogenesis of a subset of high-grade B cell non-Hodgkin lymphoma. The N-terminal segment involved in the translocation includes the region that shares a strong sequence similarity with those of BCL7B and BCL7C. Two transcript variants encoding different isoforms have been found for this gene.
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Liang, X.S., et al. Br. J. Haematol. 146(4):418-423(2009)
Morton, L.M., et al. Cancer Epidemiol. Biomarkers Prev. 18(4):1259-1270(2009)
Carbone, A., et al. Genes Chromosomes Cancer 47(12):1067-1075(2008)
Matsuoka, S., et al. Science 316(5828):1160-1166(2007)
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