|Application ||WB, IHC-P, E|
|Other Accession||NP_001106834.1, NP_001106832.1, NP_065824.2|
|Calculated MW||78137 Da|
|Antigen Region||259-286 aa|
|Other Names||TBC1 domain family member 14, TBC1D14, KIAA1322|
|Target/Specificity||This TBC14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-286 amino acids from the Central region of human TBC14.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TBC14 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Negative regulator of starvation-induced autophagosome formation.|
|Cellular Location||Golgi apparatus, cis-Golgi network. Golgi apparatus, trans-Golgi network. Note=After amino acid starvation, Golgi apparatus-associated protein levels increase compared with fed conditions. May be cycling between the Golgi apparatus and an endosomal pool, redistributing to the Golgi apparatus upon starvation|
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Provided below are standard protocols that you may find useful for product applications.
May act as a GTPase-activating protein for Rab family protein(s) (By similarity).
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)
Tempel, W., et al. Proteins 71(1):497-502(2008)
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