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TBC14 Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P, WB, E |
|---|---|
| Primary Accession | Q9P2M4 |
| Other Accession | NP_001106834.1, NP_001106832.1, NP_065824.2 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 78137 Da |
| Antigen Region | 259-286 aa |
| Gene ID | 57533 |
|---|---|
| Other Names | TBC1 domain family member 14, TBC1D14, KIAA1322 |
| Target/Specificity | This TBC14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 259-286 amino acids from the Central region of human TBC14. |
| Dilution | WB~~1:1000 IHC-P~~1:50~100 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TBC14 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TBC1D14 |
|---|---|
| Synonyms | KIAA1322 |
| Function | Plays a role in the regulation of starvation-induced autophagosome formation (PubMed:22613832). Together with the TRAPPIII complex, regulates a constitutive trafficking step from peripheral recycling endosomes to the early Golgi, maintaining the cycling pool of ATG9 required for initiation of autophagy. |
| Cellular Location | Golgi apparatus, cis-Golgi network. Golgi apparatus, trans-Golgi network Note=After amino acid starvation, Golgi apparatus-associated protein levels increase compared with fed conditions. May be cycling between the Golgi apparatus and an endosomal pool, redistributing to the Golgi apparatus upon starvation |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
May act as a GTPase-activating protein for Rab family protein(s) (By similarity).
References
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Ishibashi, K., et al. Genes Cells 14(1):41-52(2009)
Tempel, W., et al. Proteins 71(1):497-502(2008)
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