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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   UPP2 Antibody (C-term)   

UPP2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - UPP2 Antibody  (C-term) AP10995b
    UPP2 Antibody (C-term) (Cat. #AP10995b) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the UPP2 antibody detected the UPP2 protein (arrow).
  • IHC-P - UPP2 Antibody  (C-term) AP10995b
    UPP2 antibody (C-term) (Cat. #AP10995b) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the UPP2 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession O95045
Other Accession Q8CGR7, NP_001128570.1, NP_775491.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 35527 Da
Antigen Region 217-244 aa
Additional Information
Gene ID 151531
Other Names Uridine phosphorylase 2, UPase 2, UrdPase 2, UPP2
Target/Specificity This UPP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 217-244 amino acids from the C-terminal region of human UPP2.
Dilution WB~~1:1000
IHC-P~~1:50~100
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUPP2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UPP2
Function Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.
Tissue Location Predominantly expressed in kidney.
Research Areas
Citations (0)

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Background

Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose-or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Shows substrate specificity and accept uridine, deoxyuridine, and thymidine as well as the two pyrimidine nucleoside analogs 5-fluorouridine and 5-fluoro-2(')-deoxyuridine as substrates.

References

Maestrini, E., et al. Mol. Psychiatry 15(9):954-968(2010)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Johansson, M. Biochem. Biophys. Res. Commun. 307(1):41-46(2003)
Russell, R.L., et al. J. Biol. Chem. 276(16):13302-13307(2001)

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$ 295.00
$ 99.00
Cat# AP10995b
Size:
Quantity:
(40 western blots)
Availability: In Stock
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